A Case of Severe Hypertriglyceridemia in Diabetic Ketoacidosis

Choi, Seung Hwa; Sohn, Tae Seo; Lee, Jee In; Kim, Eun Sun; Choi, Woo Hwung; Shin, Ju Young; Son, Hyun Shik

Case Report

The Journal of Korean Diabetes 2008;9(4):336-340.

중증 고중성지방혈증을 동반한 당뇨병성 케톤산증 1예

최승화, 손태서, 이지인, 김은선, 최우형, 신주영, 손현식

A Case of Severe Hypertriglyceridemia in Diabetic Ketoacidosis

Seung Hwa Choi, Tae Seo Sohn, Jee In Lee, Eun Sun Kim, Woo Hwung Choi, Ju Young Shin, Hyun Shik Son

Abstract

Diabetic ketoacidosis is frequently accompanied by hypertriglyceridemia due to increased hepatic influx of free fatty acids from adipose tissue. The hypertriglyceridemia in diabetic ketoacidosis is mainly due to lipoprotein lipase deficiency and secondly to insulin deficiency. The hypertriglyceridemia responds dramatically to administration of insulin. When triglycerides exceed 1,000 mg/dL, persons are at risk for acute pancreatitis. Because of the danger of acute pancreatitis, persons with severly elevated triglycerides (>2000 mg/dL) should be treated as a medical emergency. We reported a case of diabetic ketoacidosis and severe hypertriglyceridemia (11,929 mg/dL) accompanied by lipemia retinalis. (KOREAN CLINICAL DIABETES J 9:336-340, 2008)

Key Words: Diabetic ketoacidosis, Lipemia retinalis, Severe hypertriglyceridemia