Clinical Diagnosis of Dementia.

Choi,  Seong Hye

doi:2012.13.3.133

J Korean Diabetes > Volume 13(3); 2012 > Article

Focused Issue

The Journal of Korean Diabetes 2012;13(3):133-139.
DOI: https://doi.org/10.4093/jkd.2012.13.3.133 Published online September 30, 2012.

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최성혜

Clinical Diagnosis of Dementia.

Seong Hye Choi

Department of Neurology, Inha University, School of Medicine, Incheon, Korea. seonghye@inha.ac.kr

Abstract

Cognitive function, behavioral symptoms, and activities of daily living (ADL) are all evaluated for a diagnosis of dementia. The Samsung Dementia Questionnaire (SDQ), the Short form-SDQ (S-SDQ), and the Korean Dementia Screening Questionnaire (K-DSQ) are all useful tools in the evaluation of cognitive function. The mini-mental state examination (MMSE) is the most popular tool for the measurement of general cognitive function. Objective cognitive impairment needs to be defined using neuropsychological tests. ADLs are evaluated by interview and an ADL scale such as the Korean Instrumental ADL (K-IADL) or the Seoul-IADL. Abnormal behavioral symptoms can be efficiently evaluated using the Caregiver-Administered Neuropsychiatric Inventory (CGA-NPI). The severity of dementia can be evaluated using the Clinical Dementia Rating scale or the Global Deterioration Scale. To determine the cause of dementia, neurologic examination, structural brain imaging, and blood testing, including VDRL, Vitamin B12, folate, and thyroid function tests, are administered. The new diagnosis of dementia due to Alzheimer's disease (AD) by the National Institute on Aging-Alzheimer's Association was centered on a clinical core of insidious onset and worsening of episodic memory impairment, but biomarker evidence was also integrated into the diagnosis of AD dementia for use in research setting.

Key Words: Dementia, Diagnosis, Activities of daily living, Biomarker