Diabetes and Vitamin D.

Park,  Jin Hee; Kim,  Mee Kyoung

doi:2013.14.4.190

J Korean Diabetes > Volume 14(4); 2013 > Article

Focused Issue

The Journal of Korean Diabetes 2013;14(4):190-193.
DOI: https://doi.org/10.4093/jkd.2013.14.4.190 Published online December 24, 2013.

당뇨병과 비타민 D

박진희, 김미경

Diabetes and Vitamin D.

Jin Hee Park, Mee Kyoung Kim

Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. makung@catholic.ac.kr

Abstract

Recent cross-sectional and prospective studies suggest an association between vitamin D deficiency and type 2 diabetes mellitus risk. Vitamin D metabolism may play a role in diabetes mellitus pathogenesis independently of known risk factors. The decrease in vitamin D levels may occur through several mechanisms such as a decrease in the calcium concentration, an increase in parathyroid hormones, or a direct effect of vitamin D on worsening insulin resistance and secretion, thus augmenting the risk of developing type 2 diabetes. However, doubt remains as to whether low vitamin D levels are causal or merely a marker of worse disease or worse health status. Interventional studies have provided conflicting and inconclusive results due to the different populations studies, dose and time frame of vitamin D supplementation. Further studies are required.

Key Words: Vitamin D, Diabetes mellitus, Obesity