Management of Diabetes in Organ Transplant Patients.

Yun,  Yujung; Kang,  Eun Seok

doi:2014.15.3.134

J Korean Diabetes > Volume 15(3); 2014 > Article

Statement

The Journal of Korean Diabetes 2014;15(3):134-141.
DOI: https://doi.org/10.4093/jkd.2014.15.3.134 Published online September 30, 2014.

이식환자의 당뇨병 관리

윤유정, 강은석

Management of Diabetes in Organ Transplant Patients.

Yujung Yun, Eun Seok Kang

¹Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. edgo@yuhs.ac
²Severance Hospital Diabetes Center, Seoul, Korea.
³Institute of Endocrine Research, Yonsei University College of Medicine, Seoul, Korea.

Abstract

New onset diabetes after transplantation (NODAT) is a common complication after solid-organ transplantation and is associated with increased cardiovascular morbidity, mortality, and graft loss. The risk factors for NODAT include older age, ethnicity, genetic factors,obesity, family history of diabetes, hepatitis C virus infection, and immunosuppressant use (corticosteroids, calcineurin inhibitors, and mTOR inhibitor). Management of NODAT must be considered at the pre-transplantation stage in order to properly screen high-risk patients. Although NODAT management is similar to that of general type 2 diabetes, some specific considerations must be made in NODAT management, including the interactions between anti-diabetes medication and immunosuppressive agents.

Key Words: Diabetes mellitus, Organ transplantation, Risk factors, Diagnosis, Management