The Role of the Kidney in Glucose Metabolism.

Rhee,  Sang Youl

doi:2014.15.3.142

J Korean Diabetes > Volume 15(3); 2014 > Article

Focused Issue

The Journal of Korean Diabetes 2014;15(3):142-145.
DOI: https://doi.org/10.4093/jkd.2014.15.3.142 Published online September 30, 2014.

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The Role of the Kidney in Glucose Metabolism.

Sang Youl Rhee

Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea. bard95@hanmail.net

Abstract

It is well known that the kidney is important for maintaining glucose homeostasis in vivo. However, the physiological role of the kidney in glucose metabolism is typically underestimated. Recently, a new class of anti-diabetic medications that affect the renal glucose regulatory mechanism was introduced into the market, sparking the interest of many researchers to better understand this mechanism. In this article, I briefly describe the role of the kidney in glucose metabolism and the changes of its function in patients with diabetes mellitus.

Key Words: Kidney, Glucose, Type 2 diabetes mellitus, Sodium glucose cotransporter 2, Gluconeogenesis