J Korean Diabetes > Volume 16(3); 2015 > Article
The Journal of Korean Diabetes 2015;16(3):225-229.
DOI: https://doi.org/10.4093/jkd.2015.16.3.225    Published online September 30, 2015.
고령에서 발생한 전격성 제1형 당뇨병 1예
우승민, 홍승현, 이성윤, 이수희, 이덕기, 양세정
A Case of Fulminant Type 1 Diabetes Mellitus in an Elderly Patient.
Seung Min Woo, Seung Hyun Hong, Sung Yun Lee, Su Heui Lee, Duc Ky Lee, Sae Jeong Yang
Departments of Internal Medicine, Daerim Saint Mary's Hospital, Seoul, Korea. yangsj1977@naver.com
Insulin deficiency due to destruction of pancreatic beta-cells is a typical characteristic of type 1 diabetes mellitus (DM). In 2000 Imagawa proposed a novel diagnostic model defining "fulminant type 1 DM" as developing rapidly without any evidence of autoimmunity, and ever since there have been many reports regarding the matter in Japan. In 2004, the first fulminant type 1 diabetes case was reported in Korea; however, there have been few reports since then. We present a case of a 60-year-old man who suffered from excessive thirst and polyuria after myalgia. Laboratory findings revealed a high blood glucose level and evidence of diabetic ketoacidosis, but the HbA1c level was within the normal range. The serum C-peptide level was very low and antibodies to glutamic acid decarboxylase were negative. These findings suggested fulminant type 1 diabetes. This patient has shown improvement in symptoms and examination results without complications after being treated with insulin therapy with hydration, throughout 6-months follow-up period.
Key Words: Diabetes mellitus, Diabetic ketoacidosis, Type 1

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