Therapeutic Low-density Lipoprotein (LDL) Cholesterol Goals in Patients with Diabetes Mellitus

Chang, Sang Ah

doi:2010.11.2.110

J Korean Diabetes > Volume 11(2); 2010 > Article

Focused Issue

The Journal of Korean Diabetes 2010;11(2):110-113.
DOI: https://doi.org/10.4093/kcd.2010.11.2.110

당뇨병환자에서 저밀도지질단백(LDL) 콜레스테롤의 치료목표는?

장상아

Therapeutic Low-density Lipoprotein (LDL) Cholesterol Goals in Patients with Diabetes Mellitus

Sang Ah Chang

Abstract

Lowering low density lipoprotein cholesterol (LDL-C) is the primary target for preventing cardiovascular disease (CVD). Current evidence supports that a strategy of early and aggressive lowering LDL -C level for primary and secondary prevention of CVD. Diabetic patients are highest or high risk individuals in CVD and diabetes mellitus is the coronary heart disease equivalent by National Cholesterol Education Program Adult Panel III. Therefore, based on large clinical trials, many guidelines suggest a LDL-C target is less than 100 mg/dL in diabetic patients without coronary heart disease and no additional cardio-metabolic risk factor, and less than 70 mg/dL in the patients with coronary heart disease or the patient with one or more major cardio-metabolic risk factors. (Korean Clinical Diabetes J 11:110-113, 2010)

Key Words: Cardiovascular disease, Diabetes mellitus, Dyslipidemia, LDL cholesterol