고령에서 발생한 전격성 제1형 당뇨병 1예 |
우승민, 홍승현, 이성윤, 이수희, 이덕기, 양세정 |
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A Case of Fulminant Type 1 Diabetes Mellitus in an Elderly Patient. |
Seung Min Woo, Seung Hyun Hong, Sung Yun Lee, Su Heui Lee, Duc Ky Lee, Sae Jeong Yang |
Departments of Internal Medicine, Daerim Saint Mary's Hospital, Seoul, Korea. yangsj1977@naver.com |
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Abstract |
Insulin deficiency due to destruction of pancreatic beta-cells is a typical characteristic of type 1 diabetes mellitus (DM). In 2000 Imagawa proposed a novel diagnostic model defining "fulminant type 1 DM" as developing rapidly without any evidence of autoimmunity, and ever since there have been many reports regarding the matter in Japan. In 2004, the first fulminant type 1 diabetes case was reported in Korea; however, there have been few reports since then. We present a case of a 60-year-old man who suffered from excessive thirst and polyuria after myalgia. Laboratory findings revealed a high blood glucose level and evidence of diabetic ketoacidosis, but the HbA1c level was within the normal range. The serum C-peptide level was very low and antibodies to glutamic acid decarboxylase were negative. These findings suggested fulminant type 1 diabetes. This patient has shown improvement in symptoms and examination results without complications after being treated with insulin therapy with hydration, throughout 6-months follow-up period. |
Key Words:
Diabetes mellitus, Diabetic ketoacidosis, Type 1 |
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